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The current prescribing information identifies target cells that include hepatocytes, adipocytes, myocytes, osteoblasts, and chondrocytes.¹ Through these tissues, GH participates in pathways related to: Lipid mobilization Protein metabolism Glucose regulation Tissue growth and remodeling Bone and cartilage biology Hepatic and peripheral IGF-1 production Some GH effects are mediated through IGF-1, while others result from direct GH-receptor signaling.¹ Adipose-Tissue Signaling Growth hormone has lipolytic properties, meaning it can support the mobilization of stored triglycerides from adipose tissue

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NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development